Research carried out by the department of Chemistry at Cambridge University is to be published in the Organic Process Research and Development journal.  The work involved the application of the ACR in the processing of solids under flow conditions.

The research paper entitled “Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor” ⁽¹⁾ outlines the difficulty in processing solids in continuous operation and the results of running the ACR under continuous conditions for the production of N-iodomorpholinium hydroiodide salt.

The reaction involved the formation of a suspension of solids forming a slurry which was fed into the reactor.  The reactor was required to keep the solids suspended in solution under flow conditions to avoid blockages while the reaction was carried out.  Under optimised conditions, the reaction was run for 9 hours with the Coflore ACR performing well with no blockages.

1.   Browne, D.L., et al., In Press.,  Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor, Organic Process Research and Development